Extremely elevated dosages of testosterone were required to cause the same anabolic effects in muscles of rats that were produced by low doses of Trenbolone

Trenbolone is a steroid which is used by bodybuilders for numerous years. Unfortunately, this drug has never been considered to be  a good remedy for clinical purposes. It isn’t approved for human usage by the U. S. Food and Drug Administration (FDA). This product has been demonized many times by media. A lot of articles have stated that trenbolone is very  dangerous. But recent studies have shown opposite things. It is believed that general attitude to this steroid can be soon  changed. Joshua Yarrow and his colleagues from the University of  Florida consider that this medication may be used as testosterone for hormone replacement therapy.  The experts point out that it is an effective alternative medication to testosterone for the need mentioned above. Results of studies led by these specialists have been published in the American Journal of Physiology – Endocrinology and Metabolism.
Furthermore, the specialists proclaim that trenbolone enanthate has even certain priorities over testosterone for some patients. Bodybuilders  know and support the affirmations related to this steroid. It is known that testosterone aromatases. As for trenbolone, it is converted neither to estradiol, nor to dihydrotestosterone (DHT). That’s why trenbolone doesn’t cause undesirable effects related to estrogen and DHT.
Yarrow  reports about the researches led by him and his colleagues. Castrated rats have been given trenbolone enanthate.  Even low dosages of this medicine have increased their muscle mass and kept bone mineral density. There have not been reported such adverse consequences, as enlargement of prostate or polycythemia in these lab rats.
But very enhanced measures of testosterone enanthate were required to produce the same anabolic results in muscles as were produced by reduced measures of trenbolone enanthate. But such undesirable results, as enlargement of prostate and enhanced hemoglobin accompanied the increased measures of testosterone enanthate. It is supposed by the researchers that trenbolone acts like selective androgen receptor modulators, producing anabolic effects in muscles and bones without androgenic side symptoms.
Professional competitive bodybuilders like using trenbolone several weeks before competitions because it lead to fat loss. Furthermore, the studies have shown that the same doses of trenbolone have stronger lipolytic effects than those of testosterone. It has been determined that more trenbolone an individual administrates, the greater the fat loss is caused.
Since trenbolone lacks aromatization, it is usually stacked with such steroids, as testosterone, Dianabol or with another aromatizable steroid. The lack of aromatization makes trenbolone unable to be used alone for testosterone replacement therapy. The non-aromatizable property of this steroid is responsible for just partial protection of bones.
Nevertheless, it is possible to make conclusion that additional researches are needed in order to apply trenbolone for hormone replacement therapy.